Gothenburg-based BioTech firm VERIGRAFT has been awarded a €1.2 million Eurostars grant to steer the Precision Printed Personalised Tissue Therapies (PREPPER) venture, aiming to develop next-generation 3D-printed arterial grafts.
This initiative seeks to deal with vital challenges in present graft expertise, together with restricted availability of human-donated supplies, poor integration, and excessive failure charges. The venture’s success may pave the best way for preliminary human scientific trials and future commercialisation, with potential functions extending past vascular grafts.
“This Eurostars grant is a significant milestone for VERIGRAFT and regenerative drugs. With PREPPER, we’re accelerating the way forward for personalised tissue therapies,” mentioned Dr Raimund Strehl, CTO of VERIGRAFT. “The worldwide vascular graft market is projected to exceed $4 billion by 2026, and PREPPER positions Europe on the forefront of 3D bioprinting and regenerative drugs.”
Based in 2004 by Jan Holgersson, VERIGRAFT is a biotechnology firm rooted within the Karolinska Institute, it has grown to change into a forerunner in industrialised tissue engineering and superior regenerative drugs.
The corporate has a targeted R&D pipeline of personalised tissues, focusing on areas corresponding to cardiovascular and neuronal illness. VERIGRAFT will commercialise a collection of personalised tissue-engineered grafts on a world market.
“VERIGRAFT presents a singular, breakthrough expertise within the subject of superior regenerative drugs. The expertise provides the chance to personalize tissues and organs. This may be capable to carry a paradigm shift in transplantation drugs,” mentioned Petter Björquist PhD, Chief Govt Officer.
In an ongoing trial, VERIGRAFT has efficiently transplanted their personalised tissue-engineered vein, P-TEV™, into sufferers affected by power venous insufficiency (CVI)—a situation affecting the deep venous system that results in painful swelling and ulceration of the decrease legs. Notably, one affected person in Spain can now stroll unaided for the primary time in years and attend soccer matches.
Collaborating with Readily3D SA (Switzerland), RISE (Sweden), and Sahlgrenska College Hospital (Sweden), VERIGRAFT will combine superior 3D printing, solution-blown fibre expertise, and personalised tissue engineering. The aim is to create customised vascular grafts that mimic pure arteries, providing superior sturdiness and seamless integration in comparison with present artificial options.
The PREPPER venture has acquired funding from the Eurostars-3 joint programme, with Co-funding from the European Union’s Horizon Europe analysis and innovation programme. Eurostars is a part of the European Partnership on Modern SMEs.
By leveraging this grant and collaborative experience, VERIGRAFT goals to revolutionise the sphere of regenerative drugs, offering modern options for sufferers requiring arterial grafts and positioning Europe as a frontrunner in 3D bioprinting expertise.
